The ICN2 has awarded with a Severo Ochoa Seed (SOS) Funding a collaborative project led by Dr. Salvio Suárez-García and Dr. Giulio Rosati from the Nanobioelectronics and Biosensors resesearch group. The project, entitled Mussel-inspired free-standing films as artificial biosensing skin for tissue regeneration (MlaSkin), aims to integrate functional sensors by printing methods into bioadhesive mussel-inspired membranes as artificial skin for tissue regeneration. The integrated sensors will allow the regeneration process monitoring, resulting in outstanding regenerative platforms for effective skin regeneration.
Tissue regeneration has become an essential medicine area, with the most significant effort to develop effective therapies. The challenge is twofold, not only must the damaged tissue be restored, but it must have the characteristics and functionalities of healthy tissue. This is specifically relevant for the case of skin regeneration, where the regenerated tissue must satisfy a set of requirements (e.g., robust, flexible and sensory, among others) for it to be viable and its regeneration successful. In order to overcome the current limitations, it is necessary to develop engineered materials that can act as functional platforms. With this aim, we propose the integration of sensors by printing methods into already developed mussel-inspired free-standing membranes as artificial skin for tissue regeneration. The developed membranes have demonstrated outstanding features such as biocompatibility, adhesion in humid environments and the ability to incorporate different cell types. Going a step further, we want to integrate functional sensors in order to confer sensory properties useful for the monitoring and resulting regenerated tissue. The execution of this Project will allow for producing a proof-of-concept material that integrates for the first time in a single platform the regenerative capacity and sensory abilities.
The ICN2 SOS Funding Programme was designed to support the development of novel and exploratory concepts that take excellence in new, emerging directions in research and/or original applications that bring value to European industry. The selection committee of the SOS Funding Programme this year has selected 4 projects, which will be funded with up to 20.000€. They are aimed to generate preliminary data or take first steps to proving the interest/validity of an idea while contributing to institutional Severo Ochoa objectives of the ICN2.