The Winter School was organized by Amirkabir University of Technology.
On March 4th, our group leader Prof. Daniel Ruiz-Molina, has participated as speaker in “The Virtual International Winter School on Inorganic Nanocarriers for Delivery of Therapeutic Agents: Diagnosis and Treatment”. This event is organized annually by Amirkabir University of Technology (Tehran, Iran), in an attempt for providing an opportunity for researchers and students all over the world to share the most recent progress, innovations, and ideas in this research area. Dr. Daniel Ruiz-Molina, was invited to give a talk entitled: “Functional Coordination Polymers at the Nanoscale: Old Materials New Tricks“.
The main goal of the Winter School was to examine inorganic nanoparticle-based carrier systems (gold nanoparticles, quantum dots, upconversion nanoparticles, etc.) for the delivery of therapeutic agents such as drugs, genes, and various biomolecules, with an emphasis on the structural and biological aspects. So far, huge investments, such as financial resources, materials, and even manpower, have been made to advance new therapeutic approaches for cancer. However, current clinical therapeutic choices have limited success due to tumor heterogeneity, complexity, and diversity.
Although researchers have focused on developing alternate potent, safe, and cost-effective treatments to refine the conventional cancer treatment techniques. Aversive side effects of conventional cancer therapies showed that these methods are not effective enough. Therefore, material scientists, chemists, biologists, pharmacologists, and clinicians joined to discover innovative technologies for finding effective, efficient, affordable, and acceptable cancer therapeutic options.
In the biomedical field, several nanotechnology-based approaches have influenced the development of therapeutic drugs and pharmaceutical formulations. In particular, the increasing burden to human health caused by serious diseases (e.g., various types of cancers, coronary artery disease (CAD), etc.) has required ongoing innovations in drug delivery and drug-eluting systems, many of which rely on nanotechnology.
The main applications of these new drug-delivery and targeting systems have been focused on imaging agents for cancer diagnosis and the development of new anticancer drugs and strategies. Nanocarrier-based delivery systems can be used to increase the safety and efficacy of active ingredients in medical, particularly when such ingredients are unstable, sparingly soluble, or cause off-target effects. Biocompatible inorganic material-based nanosystems provide a novel choice to effectively circumvent the intrinsic drawbacks of traditional organic materials in biomedical applications, especially in overcoming the multidrug resistance (MDR) of cancer cells due to their unique structural and compositional characteristics, for example, high stability, large surface area, tunable compositions, abundant physicochemical multi functionalities, and specific biological behaviors.
The Winter School had the participation of several international experts in the area.